@article{oai:u-nagano.repo.nii.ac.jp:00000166,
 author = {横山, 芽衣子 and 泉, 可也 and 田中, 徹 and 志塚, ふじ子},
 journal = {長野県短期大学紀要, Journal of Nagano Prefectural College},
 month = {Feb},
 note = {120005280228, application/pdf, The importance of apoptosis response on cancer cells has become a focal point of cancer research. However, little information is available on the apoptotic effects of aminolevulinic acid （ALA）. The purpose of this study was to explore the influence of ALA on HepG2 cell proliferation. HepG2 cells were cultivated for four days in media supplemented with ALA （ALA+） and without ALA （ALA-）. Phase contrast micrographs were taken every day, and the number of cells was counted. Cytochrome C oxidase activity was analyzed in the mitochondrial membrane, as well as outside the membrane. Compared with ALA-, ALA+ showed suppression of HepG2 cell proliferation and increased cytochrome C oxidase activity outside the mitochondrial membrane. The present results suggest that ALA elevate apoptosis by increasing release of cytochrome C from mitochondria.},
 pages = {23--27},
 title = {HepG2細胞の増殖抑制におけるアミノレブリン酸の効果},
 volume = {67},
 year = {2013},
 yomi = {ヨコヤマ, メイコ and イズミ, ヨシヤ and タナカ, トオル and シズカ, フジコ}
}